Opportunity Information: Apply for RFA OH 24 003
This funding opportunity (RFA OH 24 003) is a discretionary federal grant from the U.S. Department of Health and Human Services, administered through the CDCs National Institute for Occupational Safety and Health (NIOSH), to support exploratory and developmental research using the NIH-style R21 mechanism. It focuses specifically on people classified as World Trade Center (WTC) survivors under the James Zadroga 9/11 Health and Compensation Act of 2010 (Subtitle B) and related amendments. The central purpose is to fund early-stage, scientifically rigorous studies that can reduce real-world uncertainty in how WTC-related health conditions are diagnosed and treated among individuals receiving monitoring and/or clinical services through the WTC Health Program.
The research scope centers on health outcomes plausibly linked to the September 11, 2001 terrorist attacks, including both physical and mental health conditions. A key emphasis is on situations where clinicians and programs face diagnostic uncertainty (for example, how to confidently identify or distinguish WTC-related conditions) and treatment uncertainty (for example, what interventions work best, for whom, and under what circumstances). The solicitation is designed to generate practical evidence that can improve clinical decision-making within the WTC Health Program, rather than requiring that results be broadly generalizable to the general population. In other words, the research is intended first and foremost to benefit people exposed to 9/11-related hazards.
Eligible study populations include screening-eligible and certified-eligible WTC survivors, both adults and children. These are individuals who lived, worked, attended school, or were in child or adult day care in the New York City Disaster Area as defined in federal regulation (42 CFR 88.1) on 9/11 and in the aftermath, as well as those meeting eligibility criteria described in 42 CFR 88.7 or 88.8. In addition to these survivor groups, applicants may propose research that includes similarly exposed populations in New York City, including areas in Manhattan between Houston Street and 14th Street and in Brooklyn, and may include comparison or control populations. This allowance is meant to help researchers evaluate potential long-term adverse health effects across gradients of exposure, including in groups that may have been less exposed than those in the core disaster area.
A major area of interest is improving healthcare and overall well-being for survivor subpopulations that may be at higher risk or historically underrepresented in research. The announcement explicitly calls out minority groups, women who were pregnant or of reproductive age at the time of exposure, older adults, adolescents, and other children. Projects that meaningfully address barriers, disparities, or unique clinical needs in these groups fit squarely within the intent of the solicitation, especially when the work can translate into clearer diagnostic approaches or more effective treatment strategies for WTC-related conditions.
Because this is an R21, the program is aimed at the early and conceptual phases of research development. It is meant to support feasibility testing and exploration of new directions that could lead to breakthroughs, new clinical techniques, tools, methodologies, models, or other approaches with significant potential clinical impact. The solicitation also signals that applicants are expected to propose approaches where there may be minimal or no preliminary data, consistent with the R21 purpose of helping investigators test innovative ideas that are not yet fully proven but are well-justified and methodologically sound.
The opportunity is open to a broad range of applicant organizations, including various levels of government, public and private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), tribal governments and tribal organizations, public housing authorities, for-profit organizations other than small businesses, and small businesses. The CFDA (Assistance Listing) number associated with the program is 93.262, and the activity category is health. The listing indicates an expected eight awards, with applications submitted electronically and due by 5:00 pm Eastern Time on the stated closing date (December 5, 2023, for this posting). The award ceiling is listed as 0 in the record provided, which typically means applicants should rely on the full funding announcement for the specific budget limits and R21 constraints rather than the simplified listing field.
Finally, the WTC Health Program maintains a dedicated research webpage that functions as a hub for prospective applicants and ongoing investigators. It includes the programs research agenda, a publication library, and tools such as a funding dashboard that summarizes awarded projects and outputs, including research topics, populations studied, funding levels, and principal investigators and institutions. These resources are meant to help applicants align proposed projects with current program priorities, avoid duplication, and build on what is already known while still pursuing the kind of innovative, uncertainty-reducing work the R21 mechanism is intended to support.Apply for RFA OH 24 003
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Exploratory/Developmental Grants Related to the World Trade Center Survivors (R21-No Applications with Responders Accepted)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.262.
- This funding opportunity was created on Aug 18, 2023.
- Applicants must submit their applications by Dec 05, 2023 Electronically submitted applications must be submitted no later than 500 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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