Opportunity Information: Apply for RFA CE 18 003

This funding opportunity, titled "Research on Improving Pediatric mTBI Outcomes Through Clinician Training, Decision Support, and Discharge Instructions" (Funding Opportunity Number: RFA CE 18 003), is a discretionary cooperative agreement offered by the U.S. Department of Health and Human Services through the Centers for Disease Control and Prevention (CDC). It falls under the health activity category and is associated with CFDA number 93.136. The core aim is to support a rigorous research project that tests whether a specific clinical intervention can measurably improve how pediatric mild traumatic brain injury (mTBI), often referred to as concussion, is identified and managed in real-world clinical settings, specifically primary care and/or emergency departments.

The research focus is not simply on describing current practice or creating educational materials in isolation, but on evaluating an intervention with strong study design expectations. Applicants are expected to use an experimental or quasi-experimental design, meaning the project should be structured in a way that allows credible conclusions about cause and effect. In practical terms, this could involve comparing outcomes before and after implementation, using matched comparison sites, stepped-wedge rollout models, randomized approaches when feasible, or other designs that minimize bias and strengthen confidence that any observed improvements are due to the intervention itself rather than unrelated changes over time.

The intervention areas highlighted in the title clarify the types of strategies the CDC is interested in seeing tested: clinician training, clinical decision support, and discharge instructions. Clinician training generally targets improving provider knowledge and consistency in diagnosing and managing pediatric mTBI, including appropriate assessment, guidance on return to school and sports, symptom monitoring, and follow-up care. Clinical decision support typically refers to tools embedded in clinical workflow, often within electronic health records or standardized protocols, that prompt evidence-based actions such as appropriate screening, risk stratification, documentation, referral decisions, and avoidance of unnecessary imaging when not indicated. Discharge instructions are included because what families receive at the point of discharge can strongly shape recovery; clear, standardized, actionable instructions can influence adherence to rest and gradual return-to-activity recommendations, recognition of warning signs, and timely follow-up, all of which can affect outcomes.

The eligible applicant pool is broad, reflecting the applied public health and healthcare systems emphasis of the program. Eligible entities include state, county, and local governments; special district governments; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education in those categories); for-profit organizations other than small businesses; small businesses; and other organizations as clarified in the full eligibility text. In effect, the program is open to many kinds of organizations that can credibly carry out clinical research in pediatric care settings, especially those with access to primary care clinics or emergency departments where children with suspected mTBI are commonly evaluated.

From a funding and scale standpoint, the opportunity anticipates a single award (Expected Awards: 1), with an award ceiling of $550,000. That structure signals an intent to fund one lead project rather than a multi-site portfolio of smaller grants, and it places emphasis on selecting one strong, well-designed evaluation with clear implementation plans, measurable outcomes, and practical relevance to clinical practice. Because the mechanism is a cooperative agreement, the CDC typically expects to have substantial involvement compared with a standard grant, which often means closer collaboration on project direction, evaluation approach, performance monitoring, and dissemination of findings, while still leaving the recipient responsible for day-to-day execution.

Key timing information in the source data shows the opportunity was created on December 14, 2017, with an original application closing date of March 16, 2018. Applications were required to be submitted electronically by 5:00 p.m. Eastern Time on the due date. While those dates indicate the specific competition window for this announcement, the description provides a clear picture of what the CDC was seeking to fund: a carefully evaluated, workflow-relevant clinical intervention that improves the diagnosis, management, and treatment of pediatric mTBI in frontline care environments, with the ultimate goal of improving outcomes for children and adolescents after concussion.

  • The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Research on Improving Pediatric mTBI Outcomes Through Clinician Training, Decision Support, and Discharge Instructions" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.136.
  • This funding opportunity was created on Dec 14, 2017.
  • Applicants must submit their applications by Mar 16, 2018 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $550,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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