Opportunity Information: Apply for CDC RFA OE20 2001

The grant opportunity "Enhancing Public Health Laboratory Capabilities and Increasing Capacity" (CDC RFA OE20-2001) is a CDC cooperative agreement designed to strengthen public health laboratories across the United States, not just as individual organizations but as an interconnected national system that supports surveillance, routine testing, and emergency response. The overall purpose is to make public health laboratories more effective, timely, and reliable contributors to public health decision-making, including informing guidelines and policies and serving as an early warning system for emerging or unexpected threats that could affect the nations health.

The NOFO focuses on building laboratory strength through four broad strategy categories that cover the full scope of how modern public health labs operate. First, it emphasizes science, management, and operations, meaning the technical and organizational foundations needed to deliver high-quality testing and services at scale. Second, it targets policy, partnership, and communication, reflecting the reality that laboratory impact depends heavily on coordination with health departments, clinical partners, federal agencies, and other stakeholders, as well as clear communication of results and implications. Third, it prioritizes training and capacity building to expand and sustain the workforce and ensure laboratorians can keep pace with evolving methods and threats. Fourth, it advances laboratory quality, safety, and informatics, tying together rigorous quality systems, safe practices, and strong data capabilities so results can be trusted, shared, and used quickly for public health action.

These strategies are carried out through nine specific focus areas that translate the broad goals into practical domains of work. The focus areas include foundational leadership and support, which centers on the core coordination and governance functions that keep labs aligned and capable over time. Environmental health work addresses laboratory services related to environmental exposures and hazards. Foodborne, waterborne, and environmentally transmitted diseases covers testing and surveillance connected to contamination and transmission through food and water systems. Infectious diseases supports laboratory readiness and capability for detecting and monitoring pathogens of public health concern. Informatics concentrates on laboratory data systems, interoperability, and the ability to move information efficiently for surveillance and response. Newborn screening and genetics supports specialized programs that detect conditions early in life and rely on consistent quality and specialized expertise. Preparedness and response strengthens the ability of laboratory networks to surge, coordinate, and deliver reliable testing during emergencies. Quality and safety systems focus on the policies, procedures, and continuous improvement structures that protect staff and ensure dependable results. Workforce development aims to recruit, retain, train, and develop laboratorians and future leaders, addressing long-term sustainability challenges.

This funding is structured as a cooperative agreement, meaning CDC expects substantial involvement in program oversight and implementation rather than simply awarding funds and stepping back. The work is intended to build scientific knowledge and strengthen partnerships across the public health laboratory community, while also expanding the use of informatics to improve speed, consistency, and usability of laboratory data. A major theme is ensuring that laboratory networks stay positioned at the front lines of emerging threats, functioning as sentinel systems that can detect conditions that may harm population health and support rapid public health action.

The opportunity is a single-source award with only one eligible applicant: the Association of Public Health Laboratories (APHL). The NOFO explains that this limitation is based on APHLs existing role and capacity, including deep expertise in public health laboratory practice, a demonstrated history of successful partnerships with public health laboratories, recognized credibility and influence within the laboratory community, and a track record of improving laboratory practice through training, continuing education, career promotion, and leadership development. APHL had also previously been funded under an earlier five-year cooperative agreement (CDC-RFA-OE15-1501) that began July 1, 2015, and this NOFO builds on that established foundation.

Evaluation and accountability are built into the design. CDCs evaluation and performance measurement approach includes both process evaluation (whether planned activities are being implemented effectively) and outcome evaluation (whether those activities produce measurable improvements). The NOFO indicates that strategies and intended outcomes will be mapped through a Logic Model, and each focus area will have a dedicated Evaluation and Performance Measurement Plan with defined performance measures. Ongoing monitoring includes routine work plans and progress reporting, tracking performance measures, financial reporting, conference calls, and site visits. Any data collection requirements during the project period are subject to Office of Management and Budget review and approval, consistent with federal grants requirements. Post-award monitoring is framed around tracking progress toward outcomes, ensuring recipients data systems are adequate to generate reliable reports, and maintaining an environment that supports integrity in program performance and results.

In practical terms, the program is meant to drive near-term improvements (proximal outcomes) and mid-range improvements (intermediate outcomes) that, over time, strengthen the effectiveness of public health laboratories nationwide. By enhancing technical capability, improving quality and safety systems, expanding workforce capacity, and strengthening partnerships and data systems, the cooperative agreement aims to ensure laboratories can support day-to-day public health needs while also scaling rapidly and coordinating effectively during public health emergencies. Key administrative details include an award ceiling of $100,000,000, an expected number of awards of 1, the administering agency being the Department of Health and Human Services Centers for Disease Control and Prevention (CSELS), and the CFDA listing of 93.322. The original application closing date was February 5, 2020, with electronic submissions due by 11:59 p.m. Eastern Time on the due date.

  • The Department of Health and Human Services, Centers for Disease Control - CSELS in the health sector is offering a public funding opportunity titled "Enhancing Public Health Laboratory Capabilities and Increasing Capacity" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.322.
  • This funding opportunity was created on Oct 24, 2019.
  • Applicants must submit their applications by Feb 05, 2020 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $100,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for CDC RFA OE20 2001

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