Limited Competition: Development and Renovation of Housing, Breeding, and Research Spaces for Existing NIH-supported NHP Colonies (C06 Clinical Trial Not Allowed) | PAR 21 363

Opportunity Information: Apply for PAR 21 363

The National Institutes of Health (NIH) funding opportunity titled "Limited Competition: Development and Renovation of Housing, Breeding, and Research Spaces for Existing NIH-supported NHP Colonies (C06 Clinical Trial Not Allowed)" (Funding Opportunity Number PAR-21-363) is a discretionary grant program focused on improving the physical infrastructure used for non-human primate (NHP) research. The central goal is to support qualified institutions in developing new space or renovating existing space used for housing, breeding, and research activities involving NHPs. The program is meant to strengthen the capacity and readiness of NIH-supported primate colonies to meet the demands of basic research as well as translational, clinical, and social or behavioral science research that depends on NHP resources.

A key feature of this announcement is that it is a limited competition targeted specifically to facilities that already have NIH support for NHP colonies. In other words, it is not a general open call for any organization that wants to start an NHP program; it is designed to enhance and modernize existing, NIH-backed primate research infrastructure. Applications are expected to be driven by clear need: any proposed construction, development, or renovation must be justified in terms of current research requirements and well-supported projections of anticipated future research needs. That emphasis on justification signals that applicants should be prepared to connect facility upgrades directly to programmatic demand, scientific use cases, animal care requirements, and the institution's ability to support NIH-funded research over time.

The mechanism listed is a grant under the C06 activity (a type of NIH construction-related award), and the notice explicitly states "Clinical Trial Not Allowed." That means the award itself is not intended to support clinical trials as a funded activity under this mechanism. Instead, the focus is on capital improvements and research-enabling infrastructure that supports a broad research portfolio, including clinical research more generally, but not clinical trials as defined under NIH policy for this award line. The funding activity category is Health and the CFDA number associated with this opportunity is 93.352, placing it within NIH's assistance listings related to construction and improvement programs that support biomedical and behavioral research capacity.

Eligible applicants span a wide range of U.S.-based organization types and government entities, reflecting NIH's typical inclusion of public sector, higher education, nonprofit, and certain for-profit entities when they have the appropriate capabilities and mission alignment. Eligible domestic applicants include state governments, county governments, city or township governments, special district governments, and independent school districts, as well as public and state-controlled institutions of higher education and private institutions of higher education. Tribal eligibility includes federally recognized Native American tribal governments and tribal organizations other than federally recognized tribal governments, along with public housing authorities and Indian housing authorities. Nonprofit eligibility includes both 501(c)(3) organizations and nonprofits without 501(c)(3) status (in both cases, other than institutions of higher education). For-profit organizations other than small businesses and small businesses are also listed as eligible, along with an "Others" category that NIH often uses to encompass additional domestic organizational structures that meet federal requirements and the FOA's intent.

The announcement also calls out several categories of institutions and organizations as "other eligible applicants," highlighting NIH's interest in broad institutional participation where appropriate and consistent with the limited-competition scope. These include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). It also mentions eligible agencies of the federal government, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions, as well as Indian/Native American tribal governments that are not federally recognized. These categories matter because they signal NIH's willingness to receive applications from a wide spectrum of domestic institutions, provided they meet the program's central condition of being tied to existing NIH-supported NHP colony facilities and can justify the proposed infrastructure work.

Foreign participation is explicitly restricted. While the text lists "Non-domestic (non-U.S.) Entities (Foreign Organizations)" in the additional categories, it then clearly states that non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, and non-domestic components of U.S. organizations are not eligible to apply. It further states that foreign components, as defined in the NIH Grants Policy Statement, are not allowed. Practically, this means the applicant organization must be domestic, the work supported by the award must be carried out in eligible domestic components, and the funded project cannot include a foreign component as NIH defines it for grants policy purposes.

From an administrative standpoint, the opportunity is issued by the National Institutes of Health. The original closing date listed in the source data is March 15, 2022, and the creation date is January 5, 2022. The award ceiling and expected number of awards are not specified in the provided source fields, which typically means applicants would need to consult the full FOA text and any related NIH Guide notices for details on budget limits, anticipated funding levels, project periods, cost principles, and allowable and unallowable costs specific to C06 construction-related grants.

In practical terms, this FOA is best understood as an infrastructure investment program aimed at ensuring that NIH-supported primate research colonies have adequate, modern, and appropriately designed environments for animal housing and breeding, as well as functional research spaces that enable high-quality, compliant scientific work. The most competitive applications under a program like this are usually those that tightly connect the physical project to documented research demand, demonstrate readiness and feasibility (for example, planning, design status, timelines, and institutional support), and show how the improved spaces will strengthen the reliability, capacity, and sustainability of NHP-based research that NIH already supports.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition: Development and Renovation of Housing, Breeding, and Research Spaces for Existing NIH-supported NHP Colonies (C06 Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.352.
• This funding opportunity was created on 2022-01-05.
• Applicants must submit their applications by 2022-03-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 21 363

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