Opportunity Information: Apply for RFA NS 17 022
This funding opportunity, titled "Data Management and Coordinating Center (DMCC) for the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Collaborative Research Centers (CRC) (U24)," is a National Institutes of Health (NIH) cooperative agreement designed to stand up a central hub that supports a broader network of ME/CFS Collaborative Research Centers. The main idea is that, alongside multiple research centers doing scientific and clinical work on ME/CFS, there needs to be a dedicated coordinating and data infrastructure center that makes the network function smoothly, consistently, and efficiently. The DMCC is meant to be that backbone, providing shared systems, standards, and coordination so that work happening at different sites can be integrated, compared, and leveraged across the network rather than remaining siloed.
The FOA emphasizes that the DMCC will focus on infrastructure and support for the individual ME/CFS CRCs and their activities. In practical terms, this means building and running the data management capabilities that allow centers to collect clinical and research data in a consistent way, store it securely, curate it so it is usable, and then enable appropriate analysis, mining, and sharing. Clinical data management is highlighted as a core function, with an explicit goal of making data collection efficient and high quality, which usually implies standardized data elements, harmonized forms and procedures, clear data dictionaries, quality control checks, and processes for timely data submission and cleaning. Beyond basic storage, the opportunity also calls out data mining and data sharing, pointing to a role for the DMCC in making the network's data findable and usable for broader scientific discovery while still meeting privacy, ethics, and regulatory requirements.
A key purpose of creating this DMCC is to strengthen the CRC network's ability to do three major kinds of work. First, the network is intended to facilitate collaborative basic and/or clinical research on ME/CFS, which implies cross-center alignment on measures, shared protocols where appropriate, and mechanisms to coordinate multi-site projects. Second, the CRCs are expected to conduct longitudinal studies of individuals with ME/CFS, both within each center and across centers, which increases the importance of consistent follow-up schedules, shared outcome measures, and the ability to merge or compare datasets over time. Third, the network aims to expand access to information related to ME/CFS for a wide audience that includes basic and clinical researchers, academic and practicing physicians, healthcare professionals, patients, and the general public. That third aim signals that the DMCC may also support outward-facing dissemination functions, such as maintaining a website or portal, distributing network updates, and providing resources that translate research outputs into accessible information, though the exact scope would be defined by the cooperative agreement and the network's governance.
This opportunity is issued by the U.S. Department of Health and Human Services through the NIH, and it is categorized as a discretionary grant using a cooperative agreement mechanism (U24). A cooperative agreement typically means the funding agency expects to have substantial involvement in the project, not just provide funds and step back. In a networked program like this, that generally translates into NIH program staff participating in coordination, setting expectations for milestones and deliverables, and helping align the DMCC's operations with the needs of the CRCs and the overall program goals.
The FOA lists a broad set of eligible applicants, including various levels of government (state, county, city/township), special district governments, independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, other tribal organizations, public housing authorities/Indian housing authorities, nonprofit organizations (both with and without 501(c)(3) status, excluding higher education institutions in those categories), for-profit organizations other than small businesses, small businesses, and other entities as clarified in the full eligibility text. This wide eligibility suggests the NIH is primarily focused on finding an organization with the capability to run a sophisticated, compliant, and collaborative data and coordination operation, rather than limiting eligibility to one institutional type.
From the provided details, the funding opportunity number is RFA-NS-17-022, and it was created on January 27, 2017, with an original closing date of May 2, 2017. The award ceiling is listed as $750,000, and the FOA anticipated making one award, indicating a single DMCC would be selected to serve the entire CRC network. The listing includes multiple CFDA numbers (including 93.213, 93.233, 93.273, 93.279, 93.350, 93.837, 93.838, 93.839, 93.840, 93.846, 93.853, 93.855, 93.856), reflecting the NIH's cataloging and potential institute or programmatic connections relevant to the initiative.
Overall, the opportunity is best understood as funding for the central operating and data engine of an ME/CFS research network. Rather than being primarily a discovery science award, it is structured to ensure that the clinical and research data generated by multiple ME/CFS Collaborative Research Centers are collected in a rigorous, standardized manner; managed securely and efficiently; and made usable for cross-site collaboration, longitudinal analysis, and broader data-driven advances. The DMCC is expected to make the network more than the sum of its parts by enabling coordinated multi-center work, improving data comparability, supporting responsible sharing and secondary use, and helping deliver ME/CFS-related information to both professional and public audiences.Apply for RFA NS 17 022
- The Department of Health and Human Services, National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Data Management and Coordinating Center (DMCC) for the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Collaborative Research Centers (CRC) (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213, 93.233, 93.273, 93.279, 93.350, 93.837, 93.838, 93.839, 93.840, 93.846, 93.853, 93.855, 93.856.
- This funding opportunity was created on Jan 27, 2017.
- Applicants must submit their applications by May 02, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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